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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
16.06
Human Site:
S73
Identified Species:
27.18
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S73
A
V
C
A
D
P
C
S
L
I
P
T
P
D
K
Chimpanzee
Pan troglodytes
XP_512559
393
44800
R67
P
D
K
E
D
D
D
R
V
Y
P
N
S
T
C
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S73
T
G
C
A
D
P
C
S
L
I
P
T
P
D
K
Dog
Lupus familis
XP_541724
456
51105
S119
P
A
C
E
N
P
C
S
L
I
P
T
P
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S70
S
A
C
V
D
P
C
S
F
I
P
T
P
N
K
Rat
Rattus norvegicus
P39949
411
47463
S73
S
A
C
V
D
P
C
S
F
I
P
T
P
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
I71
T
G
G
I
S
P
C
I
I
I
E
T
P
H
K
Chicken
Gallus gallus
P49707
407
46720
M70
N
I
N
K
D
P
H
M
L
I
P
T
P
D
K
Frog
Xenopus laevis
Q91780
408
47153
L72
T
C
K
S
P
H
K
L
I
P
T
P
E
K
E
Zebra Danio
Brachydanio rerio
P47794
410
46612
P75
P
C
R
R
I
P
T
P
D
E
V
E
E
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
H288
R
T
P
G
L
P
K
H
Q
E
Q
I
H
H
P
Honey Bee
Apis mellifera
XP_394802
457
51232
S75
S
C
T
Q
H
Q
V
S
P
L
K
E
Q
Q
E
Nematode Worm
Caenorhab. elegans
O01501
524
60567
E163
E
R
Q
D
I
E
E
E
I
E
D
D
F
D
D
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
E84
L
V
P
M
Q
T
K
E
P
S
T
P
S
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
13.3
86.6
73.3
N.A.
66.6
66.6
N.A.
40
60
0
6.6
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
20
86.6
80
N.A.
80
80
N.A.
46.6
66.6
20
6.6
N.A.
6.6
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
0
15
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
22
36
0
0
0
43
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
8
43
8
8
0
8
0
8
8
0
36
8
% D
% Glu:
8
0
0
15
0
8
8
15
0
22
8
15
15
8
22
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
8
0
0
% F
% Gly:
0
15
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
8
8
8
0
0
0
0
8
15
0
% H
% Ile:
0
8
0
8
15
0
0
8
22
50
0
8
0
0
0
% I
% Lys:
0
0
15
8
0
0
22
0
0
0
8
0
0
8
50
% K
% Leu:
8
0
0
0
8
0
0
8
29
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
0
8
0
15
0
% N
% Pro:
22
0
15
0
8
65
0
8
15
8
50
15
50
8
8
% P
% Gln:
0
0
8
8
8
8
0
0
8
0
8
0
8
8
0
% Q
% Arg:
8
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
22
0
0
8
8
0
0
43
0
8
0
0
15
0
0
% S
% Thr:
22
8
8
0
0
8
8
0
0
0
15
50
0
8
0
% T
% Val:
0
15
0
15
0
0
8
0
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _